Vol. 8, Issue 1, Part A (2026)

Background: Both low-density lipoproteins and high-density lipoproteins have been proven in epidemiologic research to be significant risk factors for cardiovascular disease.
Aim of study: To determine the relation between the level of admission high-density lipoproteins in patients with acute coronary syndrome and coronary artery lesion severity, in-hospital and one-month mortality.
Methods: A prospective study that was conducted at IBN-Albitar Center during a period of 11 months from 1^st of February 2024 till 1^st of January 2025. It included 164 patients diagnosed with acute coronary syndrome who underwent coronary angiography during hospitalization. Electrocardiogram was done for all study patients; Echocardiography was done for all patients within 24 hrs from admission. A blood sample was taken from all patients to perform investigation: Troponin level detection, s. high density lipoprotein and other lipid profile within 24 hrs from admission. The level of s. high density lipoprotein was compared according to the outcome and severity of angiography.
Results: In this study, 7.3% of study patients died during hospitalization, while no death reported during one-month of management. No statistically significant differences in means of high-density lipoprotein, low density lipoprotein, total cholesterol, and triglyceride between patients who died and patients who survived during hospitalization. Mean of high-density lipoprotein level was significantly lower in patients with LMS lesion than those without LMS lesion.
Conclusion: Lower high-density lipoproteins levels at admission in patients with acute coronary syndrome was significantly related to the presence of LMS disease. Lower high-density lipoproteins level noticed in all in-hospital deaths, however no statistically significant relation could be found.