Vol. 7, Issue 2, Part A (2025)

Introduction: Coronary artery disease is the primary cause of global morbidity and mortality, with myocardial infarction (AMI) as its most prevalent manifestation. Left ventricular (LV) diastolic dysfunction is commonly observed after acute myocardial infarction (AMI) and is a significant predictor of unfavourable remodelling, heart failure, and death. Tissue Doppler Imaging (TDI) offers a quantitative evaluation of myocardial relaxation and may address the shortcomings of traditional Doppler indices. The aim of present study is to evaluate left ventricular systolic and diastolic function by Tissue Doppler imaging after acute myocardial infarction. 
Material and methods: This cross-sectional study was performed at the Department of Cardiology for a duration of six months. A total of 128 individuals with acute myocardial infarction (within 6 months) were enrolled following the application of inclusion and exclusion criteria. A thorough echocardiographic assessment was conducted, encompassing conventional Doppler and tissue Doppler imaging (TDI) and all the parameters were measured. Statistical relationships between Em and echocardiographic parameters were examined.
Results: The average age of the study population was 47.2 ± 6.5 years, comprising 68.8% men. Decreased Em velocities were noted at all annular sites, although Am velocities remained reasonably intact. A total of 86 patients (67.2%) demonstrated diastolic dysfunction: Grade I (42.2%), Grade II (20.3%), and Grade III (4.7%), whereas 32.8% indicated normal function. Em exhibited substantial positive relationships with ejection fraction (r = 0.52, p < 0.001) and early mitral inflow velocity E (r = 0.61, p < 0.001). The correlations with isovolumic relaxation time (r = -0.12, p = 0.18) and deceleration time (r = -0.09, p = 0.27) were minor and statistically insignificant.
Conclusion: TDI is a dependable method for evaluating left ventricular diastolic function following acute myocardial infarction. The reduced Em velocity signifies both localised and global relaxation problems and exhibits a strong correlation with EF and mitral inflow velocity, underscoring its prognostic value. The restricted associations with IVRT and DT highlight the superiority of TDI compared to traditional Doppler markers in this clinical context.